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The painkiller tanezumab was not approved by the European Medicine's Agency. At the beginning of 2021, news came that tanezumab, a new pain medication, would be launched in the US and Europe.  However, in March, tanezumab suffered a setback in the United States when the US Food and Drug Administration rejected the drug for osteoarthritis pain. There was continued uncertainty about the launch of th

https://www.arthritisportal.lu.se/article/not-approved-eu-another-setback-drug-tanezumab - 2025-12-17

Tramadol is an increasingly common drug prescribed for pain. Tramadol is a synthetic opioid (manufactured in a lab) that differs somewhat in its chemical structure compared to the natural opioid codeine. Other opioids include morphine and heroin. All opioids have analgesic properties and are extremely addictive. In a new study based on primary care data from Spain, the risks of a number of side ef

https://www.arthritisportal.lu.se/article/many-risks-painkiller-tramadol - 2025-12-17

In a new meta-analysis (a compilation of results from a number of different research studies), the benefits and side effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), paracetamol, and opioids have been studied. The research study included data from 181 publications describing 192 clinical trials involving a total of over 100,000 patients. The researchers found that the NSAID etoricoxib (6

https://www.arthritisportal.lu.se/article/benefits-and-side-effects-common-pain-meds-osteoarthritis-knee-and-hip - 2025-12-17

A Chinese research group has compiled data from 88 different scientific studies on the prevalence of knee osteoarthritis. The studies were from all around the world and together included more than 10 million people. The researchers estimated that for individuals aged 40 years and older, the global prevalence of knee osteoarthritis is around 23%. This means that almost every fourth person over the

https://www.arthritisportal.lu.se/article/how-common-knee-osteoarthritis - 2025-12-17

PRP treatment (platelet-rich plasma) is a relatively new experimental treatment that is often marketed to be effective for patients with osteoarthritis. However, there is a lack of high-quality research claiming the effectiveness of the treatment. Researchers from Brazil have recently published results from a small clinical trial (including 61 patients) evaluating three different treatments. The p

https://www.arthritisportal.lu.se/article/prp-injections-no-more-effective-placebo - 2025-12-17

Doctors Jack Cush, Martin Englund, Gillian Hawker, Tihuna Neogi, and Kent Kwoh discuss the best OA research from the 2021 ACR (American College of Rheumatology) conference, including a new study indicating that the diabetes medicine metformin lowers the risk of developing osteoarthritis. Dr. Jack Cush is a professor of internal medicine at The University of Texas Southwestern Medical School, in th

https://www.arthritisportal.lu.se/article/osteoarthritis-roundtable-best-acr-conference-2021 - 2025-12-17

In a recent study, a group of scientists have evaluated the burden of osteoarthritis over the past three decades, using data from the worldwide initiative ”Global Burden of Disease study 2019.  The results show that the number of people affected by osteoarthritis has increased by about 113 percent in 30 years, from about 248 million in year 1990 to about 530 million in year 2019. The authors concl

https://www.arthritisportal.lu.se/article/increased-burden-osteoarthritis-world - 2025-12-17

Researchers from Australia have investigated the incidence of obesity in patients with OA undergoing knee replacement. In a recent study from Australia researchers have investigated the incidence of obesity in patients undergoing knee replacements because of their OA. The results were compared to the incidence of obesity in the general population. The results show that of the 56 000 patients who u

https://www.arthritisportal.lu.se/article/there-link-between-oa-and-obesity - 2025-12-17

Researchers have investigated the use of strong painkillers the years prior total knee replacement. A recent study from England and Sweden (Lund University) has investigated the number of patients with knee osteoarthritis having required treatment with opioids in the years prior to total knee replacement. Opioids are a group of strong painkillers including Morphine, Oxycodone, Tramadol and Citodon

https://www.arthritisportal.lu.se/article/frequent-use-strong-painkillers-patients-knee-osteoarthritis-years-total-knee-replacement - 2025-12-17

The aim of this thesis was to investigate imaging techniques to study tissues and degenerative changes related to knee osteoarthritis. Osteoarthritis is commonly affecting the knee joint. At a late stage of the disease, the articular cartilage that covers the bone surfaces in the joint breaks down and disappears. Other tissues are also affected, e.g., the meniscus that is important for distributin

https://www.arthritisportal.lu.se/article/doctoral-thesis-imaging-techniques-studies-knee-osteoarthritis - 2025-12-17

We interviewed a dietician to find out more about if and how your diet might affect your OA. Whether a certain diet can make a difference or even make It better when it comes to osteoarthritis (OA) is a question that has been asked several times. We spoke to a dietician called Erik Jönsson who works at several health centers in region Skåne. He has met patients with OA many times, even if that’s o

https://www.arthritisportal.lu.se/article/does-my-diet-affect-my-oa - 2025-12-17

In a recent study, researchers investigated two different ways of treating pain in patients with knee osteoarthritis. The one half got to try W-TENS and the other half received weak opioids. They studied both the efficacy and safety in both methods. Patients with nociceptive pain from their knee OA often receive weak opioids, even though it is well known that the efficacy is moderate. It is also k

https://www.arthritisportal.lu.se/article/tens-or-weak-opioids-whats-best-if-you-suffer-painful-knee-oa - 2025-12-17

Gustavo is a mechanical engineer from Colombia. During his master's studies, Gustavo got the opportunity to conduct an internship in Lausanne, Switzerland. In Lausanne, he worked in orthopedics and studied the mechanical response of knee implants for total knee replacements using numerical modeling. When Gustavo came home from Lausanne, he was offered a PhD position at the University of Eastern Fi

https://www.arthritisportal.lu.se/article/will-it-be-possible-predict-future-health-status-your-knee-tissues - 2025-12-17

A recent study from Denmark investigated which effect CBD has in hand osteoarthritis and psoriatic arthritis. For 12 weeks, one half received synthetic CBD and the other half received placebo, as an add-on to their usual analgesics. The researchers investigated more than pain relief, including sleep quality and mental health. The participants who got CBD had 20-30 mg CBD every day for 12 weeks. Th

https://www.arthritisportal.lu.se/article/cannabidiol-cbd-relieve-oa-pain-does-it-work - 2025-12-17

Researchers studied if auricular acupressure could work as pain relief in osteoarthritis patients at 65 years old or older. In the study, researchers also investigated the participants' sleep quality. All the participants were 65 years old or more and lived in nursing homes in Korea.  There is a link between osteoarthritis pain and poor sleep. According to the study, sleep quality in people withou

https://www.arthritisportal.lu.se/article/auricular-acupressure-relieve-oa-pain - 2025-12-17

It has been known for many years that movement and exercise in different forms are beneficial and can decrease pain for those with osteoarthritis. One might have to look around to find a form of exercise that fits since it is individually. Some prefer to train on their own, and others prefer training in a group. Some get offered to participate in classes led by a trainer/physiotherapist from their

https://www.arthritisportal.lu.se/article/exercise-led-trainer-instead-opioids - 2025-12-17

The Arthritis portal earlier wrote about if there is a link between osteoarthritis and other diseases, for example, cancer. In a new study, researchers investigated if there is a link between hip osteoarthritis and stroke. A stroke is a bleeding or blood clot in the brain. A stroke can cause more or less permanent damage, depending on how damaged the brain gets. There are several risk factors for

https://www.arthritisportal.lu.se/article/osteoarthritis-and-stroke-there-link - 2025-12-17

A recent study published in the British Journal of Sports Medicine, challenged the common assumption that an ACL injury cannot heal. The anterior cruciate ligament (ACL), is the main stabilising ligament in the knee. Rupture of the ACL is most common in young, active individuals, and can have devastating impacts. The most common treatment is ACL reconstruction, which is based on the assumption tha

https://www.arthritisportal.lu.se/article/new-study-finds-ruptured-acls-can-heal-without-surgery - 2025-12-17

We are following Amanda Sjögren during her Ph.D. to learn more about what she does at work and to find out the aim of her research. Researchers often start their careers with a Ph.D. Earlier this year, Amanda Sjögren began her Ph.D. in Lund at the clinical epidemiology unit, orthopedics, Lund University. During her Ph.D., we will get the opportunity to get an insight into her work and what she's a

https://www.arthritisportal.lu.se/article/reportage-get-know-phd-student-who-wants-contribute-oa-molecular-level - 2025-12-17

In the picture, you see Andrea Dell'Isola during a lecture that he was invited to give a few weeks ago. Andrea Dell'Isola, research associate and postdoc at the unit for clinical epidemiology, orthopedics, at Lund University. Andrea is also a physiotherapist and has worked clinically before starting full-time research. The lecture interested many, over 300 people sat in the audience to learn more

https://www.arthritisportal.lu.se/article/popular-lecture-andrea-dellisola - 2025-12-17